FORM 3A - Director/Chief Executive Notice - Interests in Shares of Listed Corporation
 
Form Serial Number: DA20260706E00795
1. Date of relevant event: 06/07/2026
(dd/mm/yyyy)
2. Date when director became aware of the relevant event/ interest in the shares (if later):
(dd/mm/yyyy)
3. Stock code: 03696
4. Name of listed corporation: InSilico Medicine Cayman TopCo 
5. Class of shares: Ordinary Shares 
6. Number of issued shares in class: 578,890,466
7. Name of director (English) as printed on HKID Card/Passport:
(Surname) REN
(Other names) Feng
10. Name of director (Chinese): 任峰 
11. Chinese Character Code as printed on HKID Card:
 
24. Details of relevant event:
  Brief description of relevant event Capacity in which shares were/are held Number of shares bought/sold or involved Currency of transaction On Exchange Off Exchange
Before relevant event After relevant event Highest price (per share) Average price (per share) Average consideration (per share) Consideration code
Long position 
1201The number of shares in which you are interested has reduced because:
you completed a sale of the shares
 
2101Beneficial owner
 
2101Beneficial owner
 
787,265         
 
Short position 
 
 
 
           
 
25. Total shares in listed corporation immediately before the relevant event:
 Total number of sharesPercentage figure (%)
Long position8,740,8201.51
 
26. Total shares in listed corporation immediately after the relevant event:
 Total number of sharesPercentage figure (%)
Long position7,953,5551.37
 
27. Capacity in which interests disclosed in Box 26 are held:
Code describing capacityNumber of shares
2101Beneficial owner
Long position7,478,155
2201Interest of corporation controlled by you
Long position475,400
 
28. Further information in derivative interests in listed corporation :
Derivatives code Exercise period (dd/mm/yyyy) Consideration - if derivatives granted by listed corporation Number of shares
  BeginsEndsCurrencyPrice for grantCurrencyExercise priceCurrencyPrice on assignment 
Long position
4105Unlisted derivatives - Physically settled
14/02/202113/02/2031  USD0.420  3,465,820
Long position
4105Unlisted derivatives - Physically settled
21/02/202220/02/2032  USD1.080  266,600
Long position
4105Unlisted derivatives - Physically settled
01/12/202530/11/2035  USD2.120  1,333,000
Long position
4105Unlisted derivatives - Physically settled
  USD0    1,600,080
 
29. Further information in relation to interests of children under 18 and/or spouse:
Child/SpouseName of child/spouseNumber of shares
 
 
30. Further information in relation to interests of corporations controlled by Director:
Name of controlled corporationAddress and place of incorporationName of controlling person% controlDirect interest (Y/N)Number of shares
Diamon Holdings LimitedSuite 5, Oleander Building, Port Purcell, Tortola, VG1110, British Virgin IslandsREN Feng100.00Y
Long position475,400
 
31. Further information in relation to interests held by Director jointly with another person:
Name of joint shareholderAddressNumber of shares
 
 
32. Further information from a director who is a trustee, or beneficiary of a trust, or a person who has set up a Discretionary Trust:
Names of TrustAddressStatus codeNumber of shares
  
 
33. Further information from a party to an agreement under Section 317 (Please see Notes for further information required):
Names of other partiesAddressNumber of shares
 
Total number of shares in which a director is interested under sections 317 and 318
 
34. Supplementary information: Box 28: represents (i) 5,065,420 shares to be subscribed upon full exercise of options granted under Pre-IPO Equity Incentive Plans; and (ii) 1,600,080 underlying shares to be issued upon vesting of share awards granted under Pre-IPO Equity Incentive Plans. Box 24 represents 787,265 award shares deducted pursuant to cashless vesting under Pre-IPO Equity Incentive Plans to cover tax obligations in accordance with applicable tax laws and regulations on 6 July 2026.
35. Log/Serial Number of the previous form:
36. Number of concert party document(s) under section 317 attached/uploaded:
Date of filing this Form 3A: 06/07/2026
(dd/mm/yyyy)