FORM 2 - Corporate Substantial Shareholder Notice
 
Form Serial Number: CS20261005E00022 
1. Date of relevant event: 29/09/2026
(dd/mm/yyyy)
2. Date when the substantial shareholder becomes aware of the relevant event / interest in the shares (if later):
(dd/mm/yyyy)
3. Stock code: 02186
4. Name of listed corporation: Luye Pharma Group Ltd. 
5. Class of shares: Ordinary Shares 
6. Number of issued shares in class: 3,994,515,953
7. Name of substantial shareholder: Ginkgo (PTC) Limited 
8. Registered office: Helvetia Court, South Esplanade, St Peter Port, Guernsey
9. Principal place of business in Hong Kong: N/A 
15. Exchange on which listed:
16. Name of listed parent and exchange on which parent is listed:  
17. Details of relevant event:
  Brief description of relevant event Capacity in which shares were/are held Number of shares bought/sold or involved Currency of transaction On Exchange Off Exchange
Before relevant event After relevant event Highest price (per share) Average price (per share) Average consideration (per share) Nature of consideration
Long position
Short position 
1503You ceased to have a short position of 1% or more in the shares, or the percentage level of your short position in such shares decreased because:
any other event (you must briefly describe the relevant event in the Supplementary Information box)
 
2301Trustee
 
2301Trustee
 
8,544,000           
18. Total shares immediately before the relevant event:
 Total number of sharesPercentage figure (%)
Long position1,246,108,70331.20
Short position212,229,9505.31
19. Total shares immediately after the relevant event:
 Total number of sharesPercentage figure (%)
Long position1,246,108,70331.20
Short position203,685,9505.10
20. Capacity in which interests disclosed in Box 19 are held:
Capacity codeNumber of shares
2301Trustee
Long position1,246,108,703
Short position203,685,950

21. Further information in respect of derivative interests:
Derivatives codeNumber of shares
4105Unlisted derivatives - Physically settled
Short position203,685,950
22. Further information in relation to interests of corporations controlled by substantial shareholder:
Name of controlled corporationAddress and place of incorporationName of controlling person% controlDirect interest (Y/N)Number of shares
Nelumbo Investments LimitedHelvetia Court, South Esplanade, St Peter Port, Guernsey (Guernsey)Ginkgo (PTC) Limited100.00N
Long position1,246,108,703
Short position203,685,950
Luye Life Sciences Group LtdClarendon House, 2 Church Street, Hamilton HM 11, Bermuda (Bermuda)Nelumbo Investments Limited70.00N
Long position1,246,108,703
Short position203,685,950
Luye Pharma Holdings Ltd.Cricket Square, Hutchins Drive, PO Box 2681, Grand Cayman, KY1-1111, Cayman Islands (Cayman Islands)Luye Life Sciences Group Ltd100.00N
Long position1,246,108,703
Short position203,685,950
LuYe Pharmaceutical International Co., Ltd.PO Box 309, Ugland House, Grand Cayman, KY1-1104, Cayman Islands (Cayman Islands)Luye Pharma Holdings Ltd.100.00N
Long position1,246,108,703
Short position203,685,950
LuYe Pharmaceutical Investment Co., Ltd.PO Box 309, Ugland House, Grand Cayman, KY1-1104, Cayman Islands (Cayman Islands)LuYe Pharmaceutical International Co., Ltd.100.00Y
Long position1,246,108,703
Short position203,685,950

23. Further information in relation to interests held by substantial shareholder jointly with another person:
Name of joint shareholderAddressNumber of shares
 
24. Further information from a trustee, a beneficiary of a trust, or a person who set up a discretionary trust:
Names of trustAddressStatus codeNumber of shares
  
25. Further information from a party to an agreement under Section 317 (Please see Notes for further information required):
Names of other partiesAddressNumber of shares
 
Total number of shares in which a substantial shareholder is interested under sections 317 and 318
26. Details of person(s) in accordance with whose directions the substantial shareholder or its directors are accustomed to act:
NamesAddressRelationship CodePercentage (%)
  
 
27. Supplementary information: The short position before and after the relevant event has been updated.
28. Log/Serial Number of the previous form:
29. Number of concert party document(s) under section 317 attached/uploaded:
Date of filing this Form 2: 05/10/2026
(dd/mm/yyyy)