FORM 2 - Corporate Substantial Shareholder Notice
 
Form Serial Number: CS20260904E00353 
1. Date of relevant event: 01/09/2026
(dd/mm/yyyy)
2. Date when the substantial shareholder becomes aware of the relevant event / interest in the shares (if later): 02/09/2026
(dd/mm/yyyy)
3. Stock code: 02616
4. Name of listed corporation: CSTONE PHARMACEUTICALS - B 
5. Class of shares: Ordinary Shares 
6. Number of issued shares in class: 1,596,276,652
7. Name of substantial shareholder: Morgan Stanley 
8. Registered office: 1585 Broadway, New York 10036, New York, USA
9. Principal place of business in Hong Kong: No place of business in Hong Kong 
15. Exchange on which listed: New York Stock Exchange
16. Name of listed parent and exchange on which parent is listed: Not applicable 
17. Details of relevant event:
  Brief description of relevant event Capacity in which shares were/are held Number of shares bought/sold or involved Currency of transaction On Exchange Off Exchange
Before relevant event After relevant event Highest price (per share) Average price (per share) Average consideration (per share) Nature of consideration
Long position
1311There has been a change in nature of your interest in the shares because:
you have delivered the shares to a person who had agreed to borrow them
2201Interest of corporation controlled by you
2201Interest of corporation controlled by you
 158,000 HKD
Short position 
 
 
 		            
18. Total shares immediately before the relevant event:
 Total number of sharesPercentage figure (%)
Long position87,219,1915.46
Short position7,404,6650.46
Lending Pool00.00
19. Total shares immediately after the relevant event:
 Total number of sharesPercentage figure (%)
Long position87,219,1915.46
Short position7,404,6650.46
Lending Pool00.00
20. Capacity in which interests disclosed in Box 19 are held:
Capacity codeNumber of shares
2201Interest of corporation controlled by you
Long position87,219,191
Short position7,404,665

21. Further information in respect of derivative interests:
Derivatives codeNumber of shares
4106Unlisted derivatives - Cash settled
Long position935,931
Short position3,010,210
22. Further information in relation to interests of corporations controlled by substantial shareholder:
Name of controlled corporationAddress and place of incorporationName of controlling person% controlDirect interest (Y/N)Number of shares
Morgan Stanley International Holdings Inc.1585 Broadway, New York, New York, 10036, New York. Place of incorporation: USAMorgan Stanley100.00N
Long position85,612,979
Short position7,116,479
Morgan Stanley International Limited25 Cabot Square, Canary Wharf, London, E14 4QA, Place of incorporation: UNITED KINGDOMMorgan Stanley International Holdings Inc.100.00N
Long position85,612,979
Short position7,116,479
Morgan Stanley Investments (UK)20 Bank Street, Canary Wharf, London, E14 4AD, Place of incorporation: UNITED KINGDOMMorgan Stanley International Limited100.00N
Long position85,612,979
Short position7,116,479
Morgan Stanley & Co. International plcLegal & Compliance Department, 25 Cabot Square, Canary Wharf, London, E14 4QA, Place of incorporation: UNITED KINGDOMMorgan Stanley Investments (UK)100.00Y
Long position85,612,979
Short position7,116,479
Morgan Stanley Capital Management, LLC1585 Broadway, New York, 10036, Place of incorporation: USAMorgan Stanley100.00N
Long position1,606,212
Short position288,186
Morgan Stanley & Co. LLC1585 Broadway, New York, 10036, Place of incorporation: USAMorgan Stanley Capital Management, LLC100.00Y
Long position1,552,000
Short position0
Morgan Stanley Domestic Holdings, LLC1585 Broadway, New York, 10036, Place of incorporation: USAMorgan Stanley Capital Management, LLC100.00N
Long position52,928
Short position61
Morgan Stanley Capital Services LLC1585 Broadway, New York, 10036, Place of incorporation: USAMorgan Stanley Domestic Holdings, LLC100.00Y
Long position52,928
Short position61
Morgan Stanley Bank, N.A.201 South Main Street, 5th Floor, Salt Lake City, 84111, Place of incorporation: USAMorgan Stanley Capital Management, LLC100.00Y
Long position1,284
Short position0
Morgan Stanley Investment Management Inc.1585 Broadway, New York, 10036, Place of incorporation: USAMorgan Stanley Capital Management, LLC100.00N
Long position0
Short position288,125
Morgan Stanley Alternative Investments LLCOne Tower Bridge, 100 Front Street, Suite 400, West Conshohocken, 19428, Place of incorporation: USAMorgan Stanley Investment Management Inc.100.00N
Long position0
Short position288,125
Morgan Stanley AIP GP LPOne Tower Bridge, 100 Front Street, Suite 400, West Conshohocken, 19428, Place of incorporation: USAMorgan Stanley Investment Management Inc.0.00Y
Long position0
Short position288,125
Morgan Stanley AIP GP LPOne Tower Bridge, 100 Front Street, Suite 400, West Conshohocken, 19428, Place of incorporation: USAMorgan Stanley Alternative Investments LLC100.00Y
Long position0
Short position288,125

23. Further information in relation to interests held by substantial shareholder jointly with another person:
Name of joint shareholderAddressNumber of shares
 
24. Further information from a trustee, a beneficiary of a trust, or a person who set up a discretionary trust:
Names of trustAddressStatus codeNumber of shares
  
25. Further information from a party to an agreement under Section 317 (Please see Notes for further information required):
Names of other partiesAddressNumber of shares
 
Total number of shares in which a substantial shareholder is interested under sections 317 and 3180
26. Details of person(s) in accordance with whose directions the substantial shareholder or its directors are accustomed to act:
NamesAddressRelationship CodePercentage (%)
  
 
27. Supplementary information:
28. Log/Serial Number of the previous form:
29. Number of concert party document(s) under section 317 attached/uploaded:
Date of filing this Form 2: 04/09/2026
(dd/mm/yyyy)