Hong Kong Exchanges and Clearing Limited

FORM 2 - Corporate Substantial Shareholder Notice

Form Serial Number:

CS20260814E00418

1. Date of relevant event:

11/08/2026
(dd/mm/yyyy)

2. Date when the substantial shareholder becomes aware of the relevant event / interest in the shares (if later):

13/08/2026
(dd/mm/yyyy)

3. Stock code:

02359

4. Name of listed corporation:

WuXi AppTec Co., Ltd. - H Shares

5. Class of shares:

H Shares

6. Number of issued shares in class:

510,476,909

7. Name of substantial shareholder:

JPMorgan Chase & Co.

8. Registered office:

270 Park Avenue, New York, New York, NY, 10017, United States

9. Principal place of business in Hong Kong:

N/A

15. Exchange on which listed:

New York Stock Exchange

16. Name of listed parent and exchange on which parent is listed:

N/A

17. Details of relevant event:

Brief description of relevant event

Capacity in which shares were/are held

Number of shares bought/sold or involved

Currency of transaction

On Exchange

Off Exchange

Before relevant event

After relevant event

Highest price (per share)

Average price (per share)

Average consideration (per share)

Nature of consideration

Long position

Short position

1402	You came to have a short position of 1% or more in the shares, or the percentage level of your short position in such shares increased because: you borrowed the shares under a securities borrowing and lending agreement

2201	Interest of corporation controlled by you

2201	Interest of corporation controlled by you

2,714,078

18. Total shares immediately before the relevant event:

	Total number of shares	Percentage figure (%)
Long position	52,920,961	10.36
Short position	13,592,476	2.66
Lending Pool	27,288,809	5.34

19. Total shares immediately after the relevant event:

	Total number of shares	Percentage figure (%)
Long position	54,907,807	10.75
Short position	16,306,554	3.19
Lending Pool	26,578,244	5.20

20. Capacity in which interests disclosed in Box 19 are held:

Capacity code

Number of shares

2101	Beneficial owner

Long position	13,828,052
Short position	13,453,454

2102	Investment manager

Long position	13,659,447
Short position	2,853,100

2106	Person having a security interest in shares

Long position	842,064
Short position	0

2502	Approved lending agent

Long position	26,578,244
Short position	0

21. Further information in respect of derivative interests:

Derivatives code

Number of shares

4101	Listed derivatives - Physically settled

Long position	502,500
Short position	117,000

4102	Listed derivatives - Cash settled

Long position	0
Short position	13,900

4105	Unlisted derivatives - Physically settled

Long position	424,163
Short position	1,050,854

4106	Unlisted derivatives - Cash settled

Long position	5,375,650
Short position	6,585,330

4103	Listed derivatives - Convertible instruments

Long position	7,234,500
Short position	558,241

22. Further information in relation to interests of corporations controlled by substantial shareholder:

Name of controlled corporation

Address and place of incorporation

Name of controlling person

% control

Direct interest (Y/N)

Number of shares

JPMorgan Asset Management (China) Company Limited

42F&43F 479 Lujiazui Ring Road China (Shanghai) Pilot Free Trade Zone Shanghai 200120 China

JPMorgan Asset Management Holdings Inc.

100.00

Long position	369,900
Short position	0

JPMorgan Asset Management (Taiwan) Limited

20F & 21, No.1 Song Zhi Rd, Xin Yi District, Taipei City, Taiwan. Taipei 110 Taiwan (Province of China)

JPMorgan Asset Management (Asia) Inc.

100.00

Long position	2,900
Short position	0

J.P. Morgan SE

TaunusTurm Taunustor 1 Frankfurt am Main Frankfurt 60310 Germany

J.P. Morgan International Finance Limited

100.00

Long position	5,400
Short position	0

J.P. Morgan Securities LLC

270 Park Avenue New York NY 10017 United States

J.P. Morgan Broker-Dealer Holdings Inc.

100.00

Long position	1,618,508
Short position	1,473,288

Highbridge Capital Management, LLC

390 Madison Avenue 28th Floor New York NY 10017 United States

JPMorgan Asset Management Holdings Inc.

100.00

Long position	3,123,132
Short position	2,845,400

JPMORGAN ASSET MANAGEMENT (UK) LIMITED

60 Victoria Embankment London EC4Y0JP England

JPMORGAN ASSET MANAGEMENT INTERNATIONAL LIMITED

100.00

Long position	413,524
Short position	0

J.P. Morgan Investment Management Inc.

270 Park Avenue New York NY 10017 United States

JPMorgan Asset Management Holdings Inc.

100.00

Long position	2,624,346
Short position	0

J.P. Morgan Prime Inc.

270 Park Avenue New York NY 10017 United States

J.P. Morgan Securities LLC

100.00

Long position	2,510
Short position	2,510

JPMorgan Chase Bank, National Association

1111 Polaris Parkway Columbus OH 43240 United States

JPMorgan Chase & Co.

100.00

Long position	27,202,889
Short position	0

J.P. Morgan Alternative Asset Management, Inc.

270 Park Avenue New York NY 10017 United States

JPMorgan Asset Management Holdings Inc.

100.00

Long position	0
Short position	7,700

JPMorgan Asset Management (Asia Pacific) Limited

19 & 20/F, Chater House 8 Connaught Road Central Hong Kong Hong Kong

JPMorgan Asset Management (Asia) Inc.

100.00

Long position	6,501,000
Short position	0

J.P. MORGAN SECURITIES PLC

25 Bank Street Canary Wharf London E14 5JP England

J.P. MORGAN CAPITAL HOLDINGS LIMITED

100.00

Long position	13,043,698
Short position	11,977,656

JPMorgan Asset Management Holdings Inc.

270 Park Avenue New York NY 10017 United States

JPMorgan Chase Holdings LLC

100.00

Long position	13,034,802
Short position	2,853,100

JPMorgan Chase Holdings LLC

270 Park Avenue New York NY 10017 United States

JPMorgan Chase & Co.

100.00

Long position	14,655,820
Short position	4,328,898

JPMorgan Asset Management (Asia) Inc.

270 Park Avenue New York NY 10017 United States

JPMorgan Asset Management Holdings Inc.

100.00

Long position	6,503,900
Short position	0

J.P. Morgan International Finance Limited

270 Park Avenue New York NY 10017 United States

JPMorgan Chase Bank, National Association

100.00

Long position	13,049,098
Short position	11,977,656

JPMorgan Chase Bank, National Association

1111 Polaris Parkway Columbus OH 43240 United States

JPMorgan Chase & Co.

100.00

Long position	13,049,098
Short position	11,977,656

J.P. Morgan Broker-Dealer Holdings Inc.

4 Chase Metrotech Center 4th Floor Brooklyn NY 11245 United States

JPMorgan Chase Holdings LLC

100.00

Long position	1,621,018
Short position	1,475,798

JPMORGAN ASSET MANAGEMENT INTERNATIONAL LIMITED

60 Victoria Embankment London EC4Y0JP England

JPMorgan Asset Management Holdings Inc.

100.00

Long position	413,524
Short position	0

J.P. Morgan Securities LLC

270 Park Avenue New York NY 10017 United States

J.P. Morgan Broker-Dealer Holdings Inc.

100.00

Long position	2,510
Short position	2,510

J.P. MORGAN CAPITAL HOLDINGS LIMITED

25 Bank Street Canary Wharf London E14 5JP England

J.P. Morgan International Finance Limited

100.00

Long position	13,043,698
Short position	11,977,656

23. Further information in relation to interests held by substantial shareholder jointly with another person:

Name of joint shareholder	Address	Number of shares

24. Further information from a trustee, a beneficiary of a trust, or a person who set up a discretionary trust:

Names of trust	Address	Status code	Number of shares

25. Further information from a party to an agreement under Section 317 (Please see Notes for further information required):

Names of other parties	Address	Number of shares

Total number of shares in which a substantial shareholder is interested under sections 317 and 318

26. Details of person(s) in accordance with whose directions the substantial shareholder or its directors are accustomed to act:

Names	Address	Relationship Code	Percentage (%)

27. Supplementary information:

28. Log/Serial Number of the previous form:

29. Number of concert party document(s) under section 317 attached/uploaded:

Date of filing this Form 2:

14/08/2026
(dd/mm/yyyy)