FORM 2 - Corporate Substantial Shareholder Notice
 
Form Serial Number: CS20260812E00401 
1. Date of relevant event: 11/08/2026
(dd/mm/yyyy)
2. Date when the substantial shareholder becomes aware of the relevant event / interest in the shares (if later):
(dd/mm/yyyy)
3. Stock code: 09688
4. Name of listed corporation: Zai Lab Limited 
5. Class of shares: Ordinary Shares 
6. Number of issued shares in class: 1,137,828,030
7. Name of substantial shareholder: RTW Investments, LP 
8. Registered office: Corporation Service Company, 251 Little Falls Drive, Wilmington, DE 19808, USA
9. Principal place of business in Hong Kong: None 
15. Exchange on which listed: Not Applicable
16. Name of listed parent and exchange on which parent is listed: Not Applicable 
17. Details of relevant event:
  Brief description of relevant event Capacity in which shares were/are held Number of shares bought/sold or involved Currency of transaction On Exchange Off Exchange
Before relevant event After relevant event Highest price (per share) Average price (per share) Average consideration (per share) Nature of consideration
Long position
1101The percentage level of your interest in the shares has increased because:
you purchased the shares
2102Investment manager
2102Investment manager
9,474,460 USD 26.0500 26.0500
Short position 
 
 
 
           
18. Total shares immediately before the relevant event:
 Total number of sharesPercentage figure (%)
Long position67,340,3205.97
19. Total shares immediately after the relevant event:
 Total number of sharesPercentage figure (%)
Long position76,814,7806.75
20. Capacity in which interests disclosed in Box 19 are held:
Capacity codeNumber of shares
2102Investment manager
Long position76,814,780

21. Further information in respect of derivative interests:
Derivatives codeNumber of shares
4101Listed derivatives - Physically settled
Long position76,814,780
22. Further information in relation to interests of corporations controlled by substantial shareholder:
Name of controlled corporationAddress and place of incorporationName of controlling person% controlDirect interest (Y/N)Number of shares
RTW Master Fund, Ltd190 Elgin Avenue, George Town, Grand Cayman, KY1-9008, Cayman IslandsRTW Investments, LP100.00Y
Long position37,182,930
RTW Innovation Master Fund, Ltd.190 Elgin Avenue, George Town, Grand Cayman, KY1-9008, Cayman IslandsRTW Investments, LP100.00Y
Long position31,260,060
RTW Biotech Opportunities Ltd.PO Box 650, 1st Floor, Royal Chambers, St Julian's Avenue, St Peter Port, GY1 3JX, GuernseyRTW Investments, LP100.00Y
Long position8,371,790

23. Further information in relation to interests held by substantial shareholder jointly with another person:
Name of joint shareholderAddressNumber of shares
 
24. Further information from a trustee, a beneficiary of a trust, or a person who set up a discretionary trust:
Names of trustAddressStatus codeNumber of shares
  
25. Further information from a party to an agreement under Section 317 (Please see Notes for further information required):
Names of other partiesAddressNumber of shares
 
Total number of shares in which a substantial shareholder is interested under sections 317 and 318
26. Details of person(s) in accordance with whose directions the substantial shareholder or its directors are accustomed to act:
NamesAddressRelationship CodePercentage (%)
  
 
27. Supplementary information: The relevant event was the acquisition of 947,446 U.S. dollar-denominated American Depositary Shares (ADS) in Zai Lab Limited. These shares are listed on the NASDAQ Global Market under the ticker ZLAB. Each ADS represents the right to receive, and to exercise the beneficial ownership interests in, ten ordinary shares of Zai Lab Limited. Accordingly, the equivalent number of ordinary shares listed on the Hong Stock Exchange (stock code 9688) and acquired on the relevant event is 9,474,460.
28. Log/Serial Number of the previous form:
29. Number of concert party document(s) under section 317 attached/uploaded:
Date of filing this Form 2: 12/08/2026
(dd/mm/yyyy)