FORM 2 - Corporate Substantial Shareholder Notice
 
Form Serial Number: CS20260807E00218 
1. Date of relevant event: 05/08/2026
(dd/mm/yyyy)
2. Date when the substantial shareholder becomes aware of the relevant event / interest in the shares (if later): 05/08/2026
(dd/mm/yyyy)
3. Stock code: 01355
4. Name of listed corporation: Biosysen Ltd. 
5. Class of shares: Ordinary Shares 
6. Number of issued shares in class: 1,193,065,160
7. Name of substantial shareholder: China Regenerative Medicine Tissue Engineering Limited 
8. Registered office: Intershore Chambers, P.O. Box 4342, Road Town, Tortola, British Virgin Islands
9. Principal place of business in Hong Kong: Room 1201-02, Jubilee Centre, 18 Fenwick Road, Wanchai, Hong Kong 
15. Exchange on which listed:
16. Name of listed parent and exchange on which parent is listed:  
17. Details of relevant event:
  Brief description of relevant event Capacity in which shares were/are held Number of shares bought/sold or involved Currency of transaction On Exchange Off Exchange
Before relevant event After relevant event Highest price (per share) Average price (per share) Average consideration (per share) Nature of consideration
Long position
11031The percentage level of your interest in the shares has increased because:
you became the holder of, wrote or issued equity derivatives under which (choose one):
you have a right to take the underlying shares
2201Interest of corporation controlled by you
322,580,645 HKD 0.1550
3102Assets other than cash
Short position 
 
 
 
           
18. Total shares immediately before the relevant event:
 Total number of sharesPercentage figure (%)
Long position345,929,05028.99
19. Total shares immediately after the relevant event:
 Total number of sharesPercentage figure (%)
Long position668,509,66544.11
20. Capacity in which interests disclosed in Box 19 are held:
Capacity codeNumber of shares
2201Interest of corporation controlled by you
Long position668,509,665

21. Further information in respect of derivative interests:
Derivatives codeNumber of shares
4107Unlisted derivatives - Convertible instruments
Long position322,580,645
22. Further information in relation to interests of corporations controlled by substantial shareholder:
Name of controlled corporationAddress and place of incorporationName of controlling person% controlDirect interest (Y/N)Number of shares
Osibao Cosmetics Holding LimitedIntershore Chambers, P.O. Box 4342, Road Town, Tortola, British Virgin IslandsChina Regenerative Medicine Tissue Engineering Limited100.00N
Long position668,509,665
Osibao Cosmetic International LimitedRoom 1201-02, Jubilee Centre, 18 Fenwick Road, Wan Chai, Hong KongOsibao Cosmetics Holding Limited100.00Y
Long position668,509,665

23. Further information in relation to interests held by substantial shareholder jointly with another person:
Name of joint shareholderAddressNumber of shares
 
24. Further information from a trustee, a beneficiary of a trust, or a person who set up a discretionary trust:
Names of trustAddressStatus codeNumber of shares
  
25. Further information from a party to an agreement under Section 317 (Please see Notes for further information required):
Names of other partiesAddressNumber of shares
 
Total number of shares in which a substantial shareholder is interested under sections 317 and 318
26. Details of person(s) in accordance with whose directions the substantial shareholder or its directors are accustomed to act:
NamesAddressRelationship CodePercentage (%)
  
 
27. Supplementary information: As announced by Biosysen Limited on 5 August 2026, all the conditions precedent as set out in the Subscription and Settlement Agreement have been fulfilled, and the Completion took place on 5 August 2026. Upon Completion, the Convertible Bonds in the aggregate principal amount of HK$50.0 million were issued to Osibao Cosmetics International Limited, the Subscriber.
28. Log/Serial Number of the previous form:
29. Number of concert party document(s) under section 317 attached/uploaded:
Date of filing this Form 2: 07/08/2026
(dd/mm/yyyy)