FORM 2 - Corporate Substantial Shareholder Notice
 
Form Serial Number: CS20260805E00337 
1. Date of relevant event: 31/07/2026
(dd/mm/yyyy)
2. Date when the substantial shareholder becomes aware of the relevant event / interest in the shares (if later):
(dd/mm/yyyy)
3. Stock code: 02359
4. Name of listed corporation: WuXi AppTec Co., Ltd. - H Shares 
5. Class of shares: H Shares 
6. Number of issued shares in class: 510,476,909
7. Name of substantial shareholder: FMR LLC 
8. Registered office: The Corporation Trust Center, 1209 Orange Street, Wilmington, New Castle County, Delaware 19801
9. Principal place of business in Hong Kong: N/A 
15. Exchange on which listed:
16. Name of listed parent and exchange on which parent is listed:  
17. Details of relevant event:
  Brief description of relevant event Capacity in which shares were/are held Number of shares bought/sold or involved Currency of transaction On Exchange Off Exchange
Before relevant event After relevant event Highest price (per share) Average price (per share) Average consideration (per share) Nature of consideration
Long position
1313There has been a change in nature of your interest in the shares because:
you have lent the shares under a securities borrowing and lending agreement
2201Interest of corporation controlled by you
2201Interest of corporation controlled by you
 3,000,000
Short position 
 
 
 		            
18. Total shares immediately before the relevant event:
 Total number of sharesPercentage figure (%)
Long position44,881,4818.79
19. Total shares immediately after the relevant event:
 Total number of sharesPercentage figure (%)
Long position44,881,4818.79
20. Capacity in which interests disclosed in Box 19 are held:
Capacity codeNumber of shares
2201Interest of corporation controlled by you
Long position44,881,481

21. Further information in respect of derivative interests:
Derivatives codeNumber of shares
4101Listed derivatives - Physically settled
Long position11,519
22. Further information in relation to interests of corporations controlled by substantial shareholder:
Name of controlled corporationAddress and place of incorporationName of controlling person% controlDirect interest (Y/N)Number of shares
Fidelity Management & Research Company LLCCorporation Trust Center, 1209 Orange Street, Wilmington, New Castle County, Delaware 19801, United StatesFMR LLC100.00N
Long position12,177,742
Fidelity Management & Research Company LLCCorporation Trust Center, 1209 Orange Street, Wilmington, New Castle County, Delaware 19801, United StatesFMR LLC100.00Y
Long position19,084,125
Fidelity Management & Research (Hong Kong) Limited38/F, One International Finance Centre, 1 Harbour View Street, Central, Hong KongFidelity Management & Research Company LLC100.00Y
Long position7,082,640
Fidelity (Canada) Investment Management Holdings LLCCorporation Trust Center, 1209 Orange Street, Wilmington, New Castle County, Delaware 19801Fidelity Management & Research Company LLC100.00N
Long position2,942,249
Fidelity Management & Research (Canada) ULC483 Bay Street, Suite 300, Toronto, Ontario M5G 2N7, CanadaFidelity (Canada) Investment Management Holdings LLC100.00N
Long position2,942,249
FIAM Holdings LLCThe Corporation Trust Company, 1209 Orange Street, Wilmington, DE 19801, USAFMR LLC100.00N
Long position17,219,856
Fidelity Institutional Asset Management Trust Companyc/o C T Corporation System 2 1/2 Beacon Street Concord, NH 03301-4447FIAM Holdings LLC100.00N
Long position1,225,300
Fidelity Institutional Asset Management Trust Companyc/o C T Corporation System 2 1/2 Beacon Street Concord, NH 03301-4447FIAM Holdings LLC100.00Y
Long position2,471,996
FIAM Institutional Funds Manager, LLC900 Salem Street, Smithfield, RI 02917, USAFIAM Holdings LLC 100.00N
Long position287,590
FIAM LLC900 Salem Street, Smithfield, RI 02917, USAFIAM Holdings LLC100.00N
Long position28,648
FIAM LLC900 Salem Street, Smithfield, RI 02917, USAFIAM Holdings LLC100.00Y
Long position13,515,020
FMTC Holdings LLCCorporation Trust Center, 1209 Orange Street, Wilmington, New Castle County, Delaware 19801, United StatesFMR LLC100.00N
Long position123,207
Fidelity Management Trust Company245 Summer Street, Boston, MA 02210, USAFMTC Holdings LLC100.00Y
Long position123,207
Fidelity Advisory Holdings LLC245 Summer Street, Boston, MA 02210, USAFMR LLC100.00N
Long position10,600,293
Strategic Advisers LLC245 Summer Street, Boston, MA 02210, USAFidelity Advisory Holdings LLC100.00N
Long position10,600,293
Fidelity Canada Investors LLCThe Corporation Trust Company, 1209 Orange Street, Wilmington, DE 19801, USAOwned by certain employees and shareholders of FMR LLC100.00N
Long position4,735,272
Bay Street Holdings LLCThe Corporation Trust Company, 1209 Orange Street, Wilmington, DE 19801, USAFidelity Canada Investors LLC100.00N
Long position4,735,272
483A Bay Street Holdings LPClarendon House, 2 Church Street, Hamilton, HM11 BermudaBay Street Holdings LLC18.00N
Long position4,735,272
Fidelity Canada Holdings (UK) Limited4 Cannon Street, London, EC4M 5AB483A Bay Street Holdings LP100.00N
Long position4,735,272
Fidelity Investments Canada ULC483 Bay Street, North Tower, Suite 300, Toronto, Ontario M5G 2N7, CanadaFidelity Canada Holdings (UK) Limited100.00N
Long position4,735,272

23. Further information in relation to interests held by substantial shareholder jointly with another person:
Name of joint shareholderAddressNumber of shares
 
24. Further information from a trustee, a beneficiary of a trust, or a person who set up a discretionary trust:
Names of trustAddressStatus codeNumber of shares
  
25. Further information from a party to an agreement under Section 317 (Please see Notes for further information required):
Names of other partiesAddressNumber of shares
 
Total number of shares in which a substantial shareholder is interested under sections 317 and 318
26. Details of person(s) in accordance with whose directions the substantial shareholder or its directors are accustomed to act:
NamesAddressRelationship CodePercentage (%)
  
 
27. Supplementary information:
28. Log/Serial Number of the previous form:
29. Number of concert party document(s) under section 317 attached/uploaded: 0
Date of filing this Form 2: 05/08/2026
(dd/mm/yyyy)