Hong Kong Exchanges and Clearing Limited

FORM 2 - Corporate Substantial Shareholder Notice

Form Serial Number:

CS20260723E00189

1. Date of relevant event:

20/07/2026
(dd/mm/yyyy)

2. Date when the substantial shareholder becomes aware of the relevant event / interest in the shares (if later):

22/07/2026
(dd/mm/yyyy)

3. Stock code:

02359

4. Name of listed corporation:

WuXi AppTec Co., Ltd. - H Shares

5. Class of shares:

H Shares

6. Number of issued shares in class:

510,476,909

7. Name of substantial shareholder:

JPMorgan Chase & Co.

8. Registered office:

270 Park Avenue, New York, New York, NY, 10017, United States

9. Principal place of business in Hong Kong:

N/A

15. Exchange on which listed:

New York Stock Exchange

16. Name of listed parent and exchange on which parent is listed:

N/A

17. Details of relevant event:

Brief description of relevant event

Capacity in which shares were/are held

Number of shares bought/sold or involved

Currency of transaction

On Exchange

Off Exchange

Before relevant event

After relevant event

Highest price (per share)

Average price (per share)

Average consideration (per share)

Nature of consideration

Long position

1104	The percentage level of your interest in the shares has increased because: you acquired a security interest in the shares

2201	Interest of corporation controlled by you

2201	Interest of corporation controlled by you

2,133,622

HKD

158.6000

156.2519

155.5760

3101

Cash

Short position

18. Total shares immediately before the relevant event:

	Total number of shares	Percentage figure (%)
Long position	56,057,699	10.98
Short position	12,668,109	2.48
Lending Pool	31,632,907	6.19

19. Total shares immediately after the relevant event:

	Total number of shares	Percentage figure (%)
Long position	58,191,321	11.39
Short position	15,213,285	2.98
Lending Pool	31,207,324	6.11

20. Capacity in which interests disclosed in Box 19 are held:

Capacity code

Number of shares

2101	Beneficial owner

Long position	14,297,703
Short position	13,625,285

2102	Investment manager

Long position	12,469,890
Short position	1,588,000

2106	Person having a security interest in shares

Long position	216,404
Short position	0

2502	Approved lending agent

Long position	31,207,324
Short position	0

21. Further information in respect of derivative interests:

Derivatives code

Number of shares

4101	Listed derivatives - Physically settled

Long position	502,500
Short position	117,000

4102	Listed derivatives - Cash settled

Long position	0
Short position	17,500

4105	Unlisted derivatives - Physically settled

Long position	412,641
Short position	819,635

4106	Unlisted derivatives - Cash settled

Long position	4,911,450
Short position	5,953,256

4103	Listed derivatives - Convertible instruments

Long position	5,579,391
Short position	1,086,307

22. Further information in relation to interests of corporations controlled by substantial shareholder:

Name of controlled corporation

Address and place of incorporation

Name of controlling person

% control

Direct interest (Y/N)

Number of shares

JPMorgan Asset Management (China) Company Limited

42F&43F 479 Lujiazui Ring Road China (Shanghai) Pilot Free Trade Zone Shanghai 200120 China

JPMorgan Asset Management Holdings Inc.

100.00

Long position	263,400
Short position	0

JPMorgan Asset Management (Taiwan) Limited

20F & 21, No.1 Song Zhi Rd, Xin Yi District, Taipei City, Taiwan. Taipei 110 Taiwan (Province of China)

JPMorgan Asset Management (Asia) Inc.

100.00

Long position	2,900
Short position	0

J.P. Morgan SE

TaunusTurm Taunustor 1 Frankfurt am Main Frankfurt 60310 Germany

J.P. Morgan International Finance Limited

100.00

Long position	7,800
Short position	0

J.P. Morgan Securities LLC

270 Park Avenue New York NY 10017 United States

J.P. Morgan Broker-Dealer Holdings Inc.

100.00

Long position	1,065,635
Short position	931,678

Highbridge Capital Management, LLC

390 Madison Avenue 28th Floor New York NY 10017 United States

JPMorgan Asset Management Holdings Inc.

100.00

Long position	3,009,975
Short position	1,580,300

JPMORGAN ASSET MANAGEMENT (UK) LIMITED

60 Victoria Embankment London EC4Y0JP England

JPMORGAN ASSET MANAGEMENT INTERNATIONAL LIMITED

100.00

Long position	236,724
Short position	0

J.P. Morgan Investment Management Inc.

270 Park Avenue New York NY 10017 United States

JPMorgan Asset Management Holdings Inc.

100.00

Long position	2,019,646
Short position	0

J.P. Morgan Prime Inc.

270 Park Avenue New York NY 10017 United States

J.P. Morgan Securities LLC

100.00

Long position	2,446
Short position	2,446

JPMorgan Chase Bank, National Association

1111 Polaris Parkway Columbus OH 43240 United States

JPMorgan Chase & Co.

100.00

Long position	31,696,069
Short position	0

J.P. Morgan Alternative Asset Management, Inc.

270 Park Avenue New York NY 10017 United States

JPMorgan Asset Management Holdings Inc.

100.00

Long position	0
Short position	7,700

JPMorgan Asset Management (Asia Pacific) Limited

19 & 20/F, Chater House 8 Connaught Road Central Hong Kong Hong Kong

JPMorgan Asset Management (Asia) Inc.

100.00

Long position	6,448,500
Short position	0

J.P. MORGAN SECURITIES PLC

25 Bank Street Canary Wharf London E14 5JP England

J.P. MORGAN CAPITAL HOLDINGS LIMITED

100.00

Long position	13,438,226
Short position	12,691,161

JPMorgan Asset Management Holdings Inc.

270 Park Avenue New York NY 10017 United States

JPMorgan Chase Holdings LLC

100.00

Long position	11,981,145
Short position	1,588,000

JPMorgan Chase Holdings LLC

270 Park Avenue New York NY 10017 United States

JPMorgan Chase & Co.

100.00

Long position	13,049,226
Short position	2,522,124

JPMorgan Asset Management (Asia) Inc.

270 Park Avenue New York NY 10017 United States

JPMorgan Asset Management Holdings Inc.

100.00

Long position	6,451,400
Short position	0

J.P. Morgan International Finance Limited

270 Park Avenue New York NY 10017 United States

JPMorgan Chase Bank, National Association

100.00

Long position	13,446,026
Short position	12,691,161

JPMorgan Chase Bank, National Association

1111 Polaris Parkway Columbus OH 43240 United States

JPMorgan Chase & Co.

100.00

Long position	13,446,026
Short position	12,691,161

J.P. Morgan Broker-Dealer Holdings Inc.

4 Chase Metrotech Center 4th Floor Brooklyn NY 11245 United States

JPMorgan Chase Holdings LLC

100.00

Long position	1,068,081
Short position	934,124

JPMORGAN ASSET MANAGEMENT INTERNATIONAL LIMITED

60 Victoria Embankment London EC4Y0JP England

JPMorgan Asset Management Holdings Inc.

100.00

Long position	236,724
Short position	0

J.P. Morgan Securities LLC

270 Park Avenue New York NY 10017 United States

J.P. Morgan Broker-Dealer Holdings Inc.

100.00

Long position	2,446
Short position	2,446

J.P. MORGAN CAPITAL HOLDINGS LIMITED

25 Bank Street Canary Wharf London E14 5JP England

J.P. Morgan International Finance Limited

100.00

Long position	13,438,226
Short position	12,691,161

23. Further information in relation to interests held by substantial shareholder jointly with another person:

Name of joint shareholder	Address	Number of shares

24. Further information from a trustee, a beneficiary of a trust, or a person who set up a discretionary trust:

Names of trust	Address	Status code	Number of shares

25. Further information from a party to an agreement under Section 317 (Please see Notes for further information required):

Names of other parties	Address	Number of shares

Total number of shares in which a substantial shareholder is interested under sections 317 and 318

26. Details of person(s) in accordance with whose directions the substantial shareholder or its directors are accustomed to act:

Names	Address	Relationship Code	Percentage (%)

27. Supplementary information:

28. Log/Serial Number of the previous form:

29. Number of concert party document(s) under section 317 attached/uploaded:

Date of filing this Form 2:

23/07/2026
(dd/mm/yyyy)