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Form Serial Number: |
CS20260721E00576 |
| 1.
Date of relevant event: |
20/07/2026
(dd/mm/yyyy)
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| 2.
Date when the substantial shareholder becomes aware of the relevant event / interest in the shares (if later): |
(dd/mm/yyyy)
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| 3.
Stock code: |
03696 |
| 4.
Name of listed corporation: |
InSilico Medicine Cayman TopCo |
| 5.
Class of shares: |
Ordinary Shares |
| 6.
Number of issued shares in class: |
578,890,466 |
| 7.
Name of substantial shareholder: |
Temasek Holdings (Private) Limited |
| 8.
Registered office: |
60B Orchard Road #06-18 The Atrium@Orchard Singapore 238891 |
| 9.
Principal place of business in Hong Kong: |
N.A. |
| 15.
Exchange on which listed: |
N.A. |
| 16.
Name of listed parent and exchange on which parent is listed: |
N.A. |
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| 17.
Details of relevant event: |
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Brief description of relevant event
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Capacity in which shares were/are held
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Number of shares bought/sold or involved |
Currency of transaction |
On Exchange
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Off Exchange
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| Before relevant event
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After relevant event
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Highest price (per share)
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Average price (per share)
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Average consideration (per share)
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Nature of consideration
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|
Long position |
| 1704 | Miscellaneous
Notice filed because you ceased to have a notifiable interest in the shares of the listed corporation (you must briefly describe the relevant event in the Supplementary Information box) |
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| 2201 | Interest of corporation controlled by you |
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|
1,000,000 |
HKD |
51.4000 |
49.0000 |
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| Short position |
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| 18.
Total shares immediately before the relevant event: |
| | Total number of shares | Percentage figure (%) |
| Long position | 29,907,720 | 5.17 |
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| 19.
Total shares immediately after the relevant event: |
| | Total number of shares | Percentage figure (%) |
| Long position | 28,907,720 | 4.99 |
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| 20.
Capacity in which interests disclosed in Box 19 are held: |
| Capacity code | Number of shares |
| 2201 | Interest of corporation controlled by you |
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| 21.
Further information in respect of derivative interests: |
| Derivatives code | Number of shares |
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| 22.
Further information in relation to interests of corporations controlled by substantial shareholder: |
| Name of controlled corporation | Address and place of incorporation | Name of controlling person | % control | Direct interest (Y/N) | Number of shares |
| Temasek Capital (China) Holdings Pte. Ltd. | 60B Orchard Road #06-18 The Atrium@Orchard Singapore 238891 (Singapore) | Temasek Holdings (Private) Limited | 100.00 | N | |
| Taibai Investments Pte. Ltd. | 60B Orchard Road #06-18 The Atrium@Orchard Singapore 238891 (Singapore) | Temasek Capital (China) Holdings Pte. Ltd. | 100.00 | Y | |
| Tembusu Capital Pte. Ltd. | 60B Orchard Road #06-18 The Atrium@Orchard Singapore 238891 (Singapore) | Temasek Holdings (Private) Limited | 100.00 | N | |
| Pilatus Investments Pte. Ltd. | 60B Orchard Road #06-18 The Atrium@Orchard Singapore 238891 (Singapore) | Tembusu Capital Pte. Ltd. | 100.00 | N | |
| Seviora Holdings Pte. Ltd. | 3 Fraser Street #10-22 DUO Tower Singapore 189352 (Singapore) | Pilatus Investments Pte. Ltd. | 100.00 | N | |
| Pavilion Capital Holdings Pte. Ltd. | 3 Fraser Street #10-23 DUO Tower Singapore 189352 (Singapore) | Seviora Holdings Pte. Ltd. | 100.00 | N | |
| Pavilion Capital GP Pte. Ltd. | 3 Fraser Street #10-23 DUO Tower Singapore 189352 (Singapore) | Pavilion Capital Holdings Pte. Ltd. | 100.00 | N | |
| PavCap I Feeder No. 1 LP | 3 Fraser Street #10-23 DUO Tower Singapore 189352 (Singapore) | Pavilion Capital GP Pte. Ltd. | 100.00 | N | |
| PavCap Fund I | PO Box 309 Ugland House, Grand Cayman, KY1-1104, Cayman Islands | PavCap I Feeder No. 1 LP | 100.00 | N | |
| Palace Investments Pte. Ltd. | 3 Fraser Street #10-23 DUO Tower Singapore 189352 (Singapore) | PavCap Fund I | 100.00 | Y | |
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| 23.
Further information in relation to interests held by substantial shareholder jointly with another person: |
| Name of joint shareholder | Address | Number of shares |
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| 24.
Further information from a trustee, a beneficiary of a trust, or a person who set up a discretionary trust: |
| Names of trust | Address | Status code | Number of shares |
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| 25.
Further information from a party to an agreement under Section 317 (Please see Notes for further information required): |
| Names of other parties | Address | Number of shares |
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| Total number of shares in which a substantial shareholder is interested under sections 317 and 318 | |
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| 26.
Details of person(s) in accordance with whose directions the substantial shareholder or its directors are accustomed to act: |
| Names | Address | Relationship Code | Percentage (%) |
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| 27.
Supplementary information: |
Temasek Holdings (Private) Limited ceased to have a notifiable interest in the shares as a result of the sale by Palace Investments Pte. Ltd., an independently managed Temasek portfolio company.
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| 28.
Log/Serial Number of the previous form: |
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| 29.
Number of concert party document(s) under section 317 attached/uploaded: |
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Date of filing this Form 2: |
21/07/2026
(dd/mm/yyyy)
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