FORM 2 - Corporate Substantial Shareholder Notice
 
Form Serial Number: CS20260703E00537 
1. Date of relevant event: 29/06/2026
(dd/mm/yyyy)
2. Date when the substantial shareholder becomes aware of the relevant event / interest in the shares (if later):
(dd/mm/yyyy)
3. Stock code: 09688
4. Name of listed corporation: Zai Lab Ltd. 
5. Class of shares: Ordinary Shares 
6. Number of issued shares in class: 1,137,828,030
7. Name of substantial shareholder: FMR LLC 
8. Registered office: The Corporation Trust Center, 1209 Orange Street, Wilmington, New Castle County, Delaware 19801
9. Principal place of business in Hong Kong: N/A 
15. Exchange on which listed:
16. Name of listed parent and exchange on which parent is listed:  
17. Details of relevant event:
  Brief description of relevant event Capacity in which shares were/are held Number of shares bought/sold or involved Currency of transaction On Exchange Off Exchange
Before relevant event After relevant event Highest price (per share) Average price (per share) Average consideration (per share) Nature of consideration
Long position
1316There has been a change in nature of your interest in the shares because:
any other event (you must briefly describe the relevant event in the Supplementary Information box)
2201Interest of corporation controlled by you
2201Interest of corporation controlled by you
 57,000
Short position 
 
 
 		            
18. Total shares immediately before the relevant event:
 Total number of sharesPercentage figure (%)
Long position57,408,7815.05
19. Total shares immediately after the relevant event:
 Total number of sharesPercentage figure (%)
Long position57,408,7815.05
20. Capacity in which interests disclosed in Box 19 are held:
Capacity codeNumber of shares
2201Interest of corporation controlled by you
Long position57,408,781

21. Further information in respect of derivative interests:
Derivatives codeNumber of shares
4101Listed derivatives - Physically settled
Long position28,390,930
22. Further information in relation to interests of corporations controlled by substantial shareholder:
Name of controlled corporationAddress and place of incorporationName of controlling person% controlDirect interest (Y/N)Number of shares
Fidelity Management & Research Company LLCCorporation Trust Center, 1209 Orange Street, Wilmington, New Castle County, Delaware 19801, United StatesFMR LLC100.00N
Long position18,396,409
Fidelity Management & Research Company LLCCorporation Trust Center, 1209 Orange Street, Wilmington, New Castle County, Delaware 19801, United StatesFMR LLC100.00Y
Long position19,138,659
Fidelity Management & Research (Hong Kong) Limited38/F, One International Finance Centre, 1 Harbour View Street, Central, Hong KongFidelity Management & Research Company LLC100.00N
Long position1,627,000
Fidelity Management & Research (Hong Kong) Limited38/F, One International Finance Centre, 1 Harbour View Street, Central, Hong KongFidelity Management & Research Company LLC100.00Y
Long position15,426,892
Fidelity Management & Research (Japan) LimitedKamiyacho Prime Place at 1-17, Toranomon-4-Chome, Minato-Ku, TokyoFidelity Management & Research Company LLC100.00Y
Long position1,627,000
FIAM Holdings LLCThe Corporation Trust Company, 1209 Orange Street, Wilmington, DE 19801, USAFMR LLC100.00N
Long position17,059,867
Fidelity Institutional Asset Management Trust Companyc/o C T Corporation System 2 1/2 Beacon Street Concord, NH 03301-4447FIAM Holdings LLC100.00N
Long position2,368,196
Fidelity Institutional Asset Management Trust Companyc/o C T Corporation System 2 1/2 Beacon Street Concord, NH 03301-4447FIAM Holdings LLC100.00Y
Long position2,575,682
FIAM Institutional Funds Manager, LLC900 Salem Street, Smithfield, RI 02917, USAFIAM Holdings LLC 100.00N
Long position343,310
FIAM LLC900 Salem Street, Smithfield, RI 02917, USAFIAM Holdings LLC100.00N
Long position30,718
FIAM LLC900 Salem Street, Smithfield, RI 02917, USAFIAM Holdings LLC100.00Y
Long position12,111,271
FMTC Holdings LLCCorporation Trust Center, 1209 Orange Street, Wilmington, New Castle County, Delaware 19801, United StatesFMR LLC100.00N
Long position5,186,760
Fidelity Management Trust Company245 Summer Street, Boston, MA 02210, USAFMTC Holdings LLC100.00Y
Long position5,186,760
Fidelity Advisory Holdings LLC245 Summer Street, Boston, MA 02210, USAFMR LLC100.00N
Long position6,143,330
Strategic Advisers LLC245 Summer Street, Boston, MA 02210, USAFidelity Advisory Holdings LLC100.00N
Long position6,143,330
Fidelity Canada Investors LLCThe Corporation Trust Company, 1209 Orange Street, Wilmington, DE 19801, USAOwned by certain employees and shareholders of FMR LLC100.00N
Long position691,514
Bay Street Holdings LLCThe Corporation Trust Company, 1209 Orange Street, Wilmington, DE 19801, USAFidelity Canada Investors LLC100.00N
Long position691,514
483A Bay Street Holdings LPClarendon House, 2 Church Street, Hamilton, HM11 BermudaBay Street Holdings LLC18.00N
Long position691,514
Fidelity Canada Holdings (UK) Limited4 Cannon Street, London, EC4M 5AB483A Bay Street Holdings LP100.00N
Long position691,514
Fidelity Investments Canada ULC483 Bay Street, North Tower, Suite 300, Toronto, Ontario M5G 2N7, CanadaFidelity Canada Holdings (UK) Limited100.00N
Long position691,514

23. Further information in relation to interests held by substantial shareholder jointly with another person:
Name of joint shareholderAddressNumber of shares
 
24. Further information from a trustee, a beneficiary of a trust, or a person who set up a discretionary trust:
Names of trustAddressStatus codeNumber of shares
  
25. Further information from a party to an agreement under Section 317 (Please see Notes for further information required):
Names of other partiesAddressNumber of shares
 
Total number of shares in which a substantial shareholder is interested under sections 317 and 318
26. Details of person(s) in accordance with whose directions the substantial shareholder or its directors are accustomed to act:
NamesAddressRelationship CodePercentage (%)
  
 
27. Supplementary information: Change in nature of interest triggered by recall of ADRs 227,000 shares previously lent and by lending 170,000 shares under common shares.
28. Log/Serial Number of the previous form:
29. Number of concert party document(s) under section 317 attached/uploaded: 0
Date of filing this Form 2: 03/07/2026
(dd/mm/yyyy)