Hong Kong Exchanges and Clearing Limited

FORM 2 - Corporate Substantial Shareholder Notice

Form Serial Number:

CS20230914E00451

1. Date of relevant event:

11/09/2023
(dd/mm/yyyy)

2. Date when the substantial shareholder becomes aware of the relevant event / interest in the shares (if later):

13/09/2023
(dd/mm/yyyy)

3. Stock code:

02359

4. Name of listed corporation:

WuXi AppTec Co., Ltd. - H Shares

5. Class of shares:

H Shares

6. Number of issued shares in class:

402,543,650

7. Name of substantial shareholder:

JPMorgan Chase & Co.

8. Registered office:

383 Madison Ave., New York, NY 10179, United States

9. Principal place of business in Hong Kong:

N/A

15. Exchange on which listed:

New York Stock Exchange

16. Name of listed parent and exchange on which parent is listed:

N/A

17. Details of relevant event:

Brief description of relevant event

Capacity in which shares were/are held

Number of shares bought/sold or involved

Currency of transaction

On Exchange

Off Exchange

Before relevant event

After relevant event

Highest price (per share)

Average price (per share)

Average consideration (per share)

Nature of consideration

Long position

1104	The percentage level of your interest in the shares has increased because: you acquired a security interest in the shares

2201	Interest of corporation controlled by you

2201	Interest of corporation controlled by you

3,852,054

HKD

83.3000

82.0262

82.0044

3101

Cash

Short position

1402	You came to have a short position of 1% or more in the shares, or the percentage level of your short position in such shares increased because: you borrowed the shares under a securities borrowing and lending agreement

2201	Interest of corporation controlled by you

2201	Interest of corporation controlled by you

4,002,718

18. Total shares immediately before the relevant event:

	Total number of shares	Percentage figure (%)
Long position	41,173,271	10.22
Short position	18,342,865	4.55
Lending Pool	16,631,063	4.13

19. Total shares immediately after the relevant event:

	Total number of shares	Percentage figure (%)
Long position	45,025,325	11.18
Short position	22,345,583	5.55
Lending Pool	16,129,523	4.00

20. Capacity in which interests disclosed in Box 19 are held:

Capacity code

Number of shares

2201	Interest of corporation controlled by you

Long position	21,973,648
Short position	22,345,583

2102	Investment manager

Long position	6,415,886
Short position	0

2106	Person having a security interest in shares

Long position	506,268
Short position	0

2502	Approved lending agent

Long position	16,129,523
Short position	0

21. Further information in respect of derivative interests:

Derivatives code

Number of shares

4102	Listed derivatives - Cash settled

Long position	0
Short position	4,100

4105	Unlisted derivatives - Physically settled

Long position	50,598
Short position	289,669

4106	Unlisted derivatives - Cash settled

Long position	9,842,427
Short position	620,337

22. Further information in relation to interests of corporations controlled by substantial shareholder:

Name of controlled corporation

Address and place of incorporation

Name of controlling person

% control

Direct interest (Y/N)

Number of shares

JPMorgan Asset Management (China) Company Limited

25th Floor, Aurora Plaza 99 Fu Cheng Road Pudong Shanghai 200120 China

JPMorgan Asset Management Holdings Inc.

100.00

Long position	28,280
Short position	0

JPMorgan Asset Management (Taiwan) Limited

20F & 21, No.1 Song Zhi Rd, Xin Yi District, Taipei City, Taiwan. Taipei 110 Taiwan (Province of China)

JPMorgan Asset Management (Asia) Inc.

100.00

Long position	112,800
Short position	0

J.P. Morgan Securities LLC

383 Madison Ave. New York NY 10179 United States

J.P. Morgan Broker-Dealer Holdings Inc.

100.00

Long position	5,573,244
Short position	5,367,424

JPMORGAN CHASE BANK, N.A. - LONDON BRANCH

25 Bank Street Canary Wharf London E14 5JP England

JPMorgan Chase Bank, National Association

100.00

Long position	16,129,523
Short position	0

JPMORGAN ASSET MANAGEMENT (UK) LIMITED

60 Victoria Embankment London EC4Y0JP England

JPMORGAN ASSET MANAGEMENT INTERNATIONAL LIMITED

100.00

Long position	800,032
Short position	0

J.P. Morgan Investment Management Inc.

383 Madison Avenue New York NY 10179 United States

JPMorgan Asset Management Holdings Inc.

100.00

Long position	3,370,926
Short position	0

J.P. Morgan Prime Inc.

383 Madison Avenue New York NY 10179 United States

J.P. Morgan Securities LLC

100.00

Long position	4,844
Short position	4,844

JPMorgan Asset Management (Singapore) Limited

88 Market Street 30-00 CapitaSpring Singapore 048948 Singapore

JPMorgan Asset Management (Asia) Inc.

100.00

Long position	8,500
Short position	0

JPMorgan Chase Bank, National Association

1111 Polaris Parkway Columbus OH 43240 United States

JPMorgan Chase & Co.

100.00

Long position	584,448
Short position	0

JPMorgan Asset Management (Asia Pacific) Limited

19 & 20/F, Chater House 8 Connaught Road Central Hong Kong Hong Kong

JPMorgan Asset Management (Asia) Inc.

99.99

Long position	1,510,900
Short position	0

J.P. MORGAN SECURITIES PLC

25 Bank Street Canary Wharf London E14 5JP England

J.P. MORGAN CAPITAL HOLDINGS LIMITED

100.00

Long position	16,901,828
Short position	16,973,315

JPMorgan Asset Management Holdings Inc.

383 Madison Avenue New York NY 10179 United States

JPMorgan Chase Holdings LLC

100.00

Long position	5,831,438
Short position	0

JPMorgan Chase Holdings LLC

383 Madison Avenue New York NY 10179 United States

JPMorgan Chase & Co.

100.00

Long position	11,409,526
Short position	5,372,268

JPMorgan Asset Management (Asia) Inc.

383 Madison Avenue New York NY 10179 United States

JPMorgan Asset Management Holdings Inc.

100.00

Long position	1,632,200
Short position	0

J.P. Morgan Broker-Dealer Holdings Inc.

4 Chase Metrotech Center 4th Floor Brooklyn NY 11245 United States

JPMorgan Chase Holdings LLC

100.00

Long position	5,578,088
Short position	5,372,268

JPMorgan Chase Bank, National Association

1111 Polaris Parkway Columbus OH 43240 United States

JPMorgan Chase & Co.

100.00

Long position	33,031,351
Short position	16,973,315

JPMORGAN ASSET MANAGEMENT INTERNATIONAL LIMITED

60 Victoria Embankment London EC4Y0JP England

JPMorgan Asset Management Holdings Inc.

100.00

Long position	800,032
Short position	0

J.P. Morgan Securities LLC

383 Madison Ave. New York NY 10179 United States

J.P. Morgan Broker-Dealer Holdings Inc.

100.00

Long position	4,844
Short position	4,844

J.P. MORGAN CAPITAL HOLDINGS LIMITED

25 Bank Street Canary Wharf London E14 5JP England

J.P. Morgan International Finance Limited

100.00

Long position	16,901,828
Short position	16,973,315

J.P. Morgan International Finance Limited

383 Madison Avenue New York NY 10179 United States

JPMorgan Chase Bank, National Association

100.00

Long position	16,901,828
Short position	16,973,315

23. Further information in relation to interests held by substantial shareholder jointly with another person:

Name of joint shareholder	Address	Number of shares

24. Further information from a trustee, a beneficiary of a trust, or a person who set up a discretionary trust:

Names of trust	Address	Status code	Number of shares

25. Further information from a party to an agreement under Section 317 (Please see Notes for further information required):

Names of other parties	Address	Number of shares

Total number of shares in which a substantial shareholder is interested under sections 317 and 318

26. Details of person(s) in accordance with whose directions the substantial shareholder or its directors are accustomed to act:

Names	Address	Relationship Code	Percentage (%)

27. Supplementary information:

28. Log/Serial Number of the previous form:

29. Number of concert party document(s) under section 317 attached/uploaded:

Date of filing this Form 2:

14/09/2023
(dd/mm/yyyy)