FORM 2 - Corporate Substantial Shareholder Notice
Form Serial Number: CS20210916E00428 
1. Date of relevant event: 16/09/2021
2. Date when the substantial shareholder becomes aware of the relevant event / interest in the shares (if later):
3. Stock code: 02126
4. Name of listed corporation: JW (Cayman) Therapeutics Co. Ltd - B 
5. Class of shares: Ordinary Shares 
6. Number of issued shares in class: 401,687,628
7. Name of substantial shareholder: Temasek Life Sciences Private Limited 
8. Registered office: 60B Orchard Road #06-18 The Atrium@Orchard Singapore 238891
9. Principal place of business in Hong Kong: NA 
15. Exchange on which listed: NA
16. Name of listed parent and exchange on which parent is listed: NA 
17. Details of relevant event:
  Brief description of relevant event Capacity in which shares were/are held Number of shares bought/sold or involved Currency of transaction On Exchange Off Exchange
Before relevant event After relevant event Highest price (per share) Average price (per share) Average consideration (per share) Nature of consideration
Long position
1205The percentage level of your interest in the shares has reduced because:
you ceased to have a security interest in the shares
2201Interest of corporation controlled by you
22,668,740 HKD 22.2000
Short position 
18. Total shares immediately before the relevant event:
 Total number of sharesPercentage figure (%)
Long position22,668,7405.64
19. Total shares immediately after the relevant event:
 Total number of sharesPercentage figure (%)
Long position00.00
20. Capacity in which interests disclosed in Box 19 are held:
Capacity codeNumber of shares

21. Further information in respect of derivative interests:
Derivatives codeNumber of shares
22. Further information in relation to interests of corporations controlled by substantial shareholder:
Name of controlled corporationAddress and place of incorporationName of controlling person% controlDirect interest (Y/N)Number of shares
TLS Beta Pte. Ltd.60B Orchard Road #06-18 The Atrium @ Orchard Singapore 238891 (Singapore)Temasek Life Sciences Private Limited100.00Y
Long position0

23. Further information in relation to interests held by substantial shareholder jointly with another person:
Name of joint shareholderAddressNumber of shares
24. Further information from a trustee, a beneficiary of a trust, or a person who set up a discretionary trust:
Names of trustAddressStatus codeNumber of shares
25. Further information from a party to an agreement under Section 317 (Please see Notes for further information required):
Names of other partiesAddressNumber of shares
Total number of shares in which a substantial shareholder is interested under sections 317 and 318
26. Details of person(s) in accordance with whose directions the substantial shareholder or its directors are accustomed to act:
NamesAddressRelationship CodePercentage (%)
27. Supplementary information:
28. Log/Serial Number of the previous form:
29. Number of concert party document(s) under section 317 attached/uploaded:
Date of filing this Form 2: 16/09/2021