FORM 1 - Individual Substantial Shareholder Notice
 
Form Serial Number: IS20260821E00177
1. Date of relevant event: 20/08/2026
(dd/mm/yyyy)
2. Date when the substantial shareholder becomes aware of the relevant event / interest in the shares (if later):
(dd/mm/yyyy)
3. Stock code: 09688
4. Name of listed corporation: Zai Lab Limited 
5. Class of shares: Ordinary Shares 
6. Number of issued shares in class: 1,137,828,030
7. Name of substantial shareholder (English) as printed on HKID Card/Passport:
(Surname) Wong
(Other names) Roderick
10. Name of substantial shareholder (Chinese):  
11. Chinese Character Code as printed on HKID Card:
 
14. Details of relevant event:
  Brief description of relevant event Capacity in which shares were/are held Number of shares bought/sold or involved Currency of transaction On Exchange Off Exchange
Before relevant event After relevant event Highest price (per share) Average price (per share) Average consideration (per share) Nature of consideration
Long position 
1101The percentage level of your interest in the shares has increased because:
you purchased the shares
 
2201Interest of corporation controlled by you
 
2201Interest of corporation controlled by you
 
12,307,220  USD  26.0000  26.0000   
 
Short position 
 
 
 
           
15. Total shares immediately before the relevant event:
 Total number of sharesPercentage figure (%)
Long position81,580,1307.17
 
16. Total shares immediately after the relevant event:
 Total number of sharesPercentage figure (%)
Long position93,887,3508.25
 
17. Capacity in which interests disclosed in Box 16 are held:
Capacity codeNumber of shares
2201Interest of corporation controlled by you
Long position93,887,350
 
18. Further information in respect of derivative interests:
Derivatives codeNumber of shares
4101Listed derivatives - Physically settled
Long position93,887,350
 
19. Further information in relation to interests of children under 18 and/or spouse:
Child/SpouseName of child/spouseNumber of shares
 
 
20. Further information in relation to interests of corporations controlled by substantial shareholder:
Name of controlled corporationAddress and place of incorporationName of controlling shareholder% controlDirect interest (Y/N)Number of shares
RTW Investments, LPCorporation Service Company, 251 Little Falls Drive, Wilmington, DE 19808, USARoderick Wong75.00N
Long position93,887,350
RTW Fund Group GP, LLCCorporation Service Company, 251 Little Falls Drive, Wilmington, DE 19808, USARoderick Wong75.00N
Long position93,887,350
RTW Master Fund, Ltd190 Elgin Avenue, George Town, Grand Cayman, KY1-9008, Cayman IslandsRTW Fund Group GP, LLC100.00Y
Long position45,465,960
RTW Innovation Master Fund, Ltd.190 Elgin Avenue, George Town, Grand Cayman, KY1-9008, Cayman IslandsRTW Fund Group GP, LLC100.00Y
Long position38,153,650
RTW Venture Performance LLCCorporation Service Company, 251 Little Falls Drive, Wilmington, DE 19808, USARTW Fund Group GP, LLC100.00N
Long position10,267,740
RTW Biotech Opportunities Ltd.PO Box 650, 1st Floor, Royal Chambers, St Julian's Avenue, St Peter Port, GY1 3JX, GuernseyRTW Venture Performance LLC100.00Y
Long position10,267,740
 
21. Further information in relation to interests held by substantial shareholder jointly with another person:
Name of joint shareholderAddressNumber of shares
 
 
22. Further information from a trustee, a beneficiary of a trust, or a person who has set up a discretionary trust:
Names of trustAddressStatus codeNumber of shares
  
 
23. Further information from a party to an agreement under Section 317 (Please see Notes for further information required):
Names of other partiesAddressNumber of shares
 
Total number of shares in which a substantial shareholder is interested under sections 317 and 318
 
24. Supplementary information: The relevant event was the acquisition of 1,230,722 U.S. dollar-denominated American Depositary Shares (ADS) in Zai Lab Limited. These shares are listed on the NASDAQ Global Market under the ticker ZLAB. Each ADS represents the right to receive, and to exercise the beneficial ownership interests in, ten ordinary shares of Zai Lab Limited. Accordingly, the equivalent number of ordinary shares listed on the Hong Stock Exchange (stock code 9688) and acquired on the relevant event is 12,307,220.
25. Log/Serial Number of the previous form:
26. Number of concert party document(s) under section 317 attached/uploaded:
Date of filing this Form 1: 21/08/2026
(dd/mm/yyyy)