FORM 1 - Individual Substantial Shareholder Notice
 
Form Serial Number: IS20260804E00183
1. Date of relevant event: 30/07/2026
(dd/mm/yyyy)
2. Date when the substantial shareholder becomes aware of the relevant event / interest in the shares (if later):
(dd/mm/yyyy)
3. Stock code: 02171
4. Name of listed corporation: CARsgen Therapeutics Holdings Ltd. - B 
5. Class of shares: Ordinary Shares 
6. Number of issued shares in class: 594,229,547
7. Name of substantial shareholder (English) as printed on HKID Card/Passport:
(Surname) Yang
(Other names) Xuehong
10. Name of substantial shareholder (Chinese): 楊雪虹 
11. Chinese Character Code as printed on HKID Card: 279971855725
 
14. Details of relevant event:
  Brief description of relevant event Capacity in which shares were/are held Number of shares bought/sold or involved Currency of transaction On Exchange Off Exchange
Before relevant event After relevant event Highest price (per share) Average price (per share) Average consideration (per share) Nature of consideration
Long position 
1213The percentage level of your interest in the shares has reduced because:
any other event (you must briefly describe the relevant event in the Supplementary Information box)
 
2501Other (you must describe the capacity in the Supplementary Information box)
 
 
7,228,000         
 
Short position 
 
 
 
           
15. Total shares immediately before the relevant event:
 Total number of sharesPercentage figure (%)
Long position225,848,73037.55
 
16. Total shares immediately after the relevant event:
 Total number of sharesPercentage figure (%)
Long position218,620,73036.79
 
17. Capacity in which interests disclosed in Box 16 are held:
Capacity codeNumber of shares
2201Interest of corporation controlled by you
Long position8,888,888
2401A concert party to an agreement to buy shares described in s.317(1)(a)
Long position209,731,842
 
18. Further information in respect of derivative interests:
Derivatives codeNumber of shares
  
 
19. Further information in relation to interests of children under 18 and/or spouse:
Child/SpouseName of child/spouseNumber of shares
 
 
20. Further information in relation to interests of corporations controlled by substantial shareholder:
Name of controlled corporationAddress and place of incorporationName of controlling shareholder% controlDirect interest (Y/N)Number of shares
Yeed Holdings LimitedVistra Corporate Services Centre, Wickhams Cay II, Road Town, Tortola, VG1110, British Virgin Islands (British Virgin Islands)Yang Xuehong100.00Y
Long position8,888,888
 
21. Further information in relation to interests held by substantial shareholder jointly with another person:
Name of joint shareholderAddressNumber of shares
 
 
22. Further information from a trustee, a beneficiary of a trust, or a person who has set up a discretionary trust:
Names of trustAddressStatus codeNumber of shares
  
 
23. Further information from a party to an agreement under Section 317 (Please see Notes for further information required):
Names of other partiesAddressNumber of shares
Guo XiaojingAddresses of individuals are not displayed.5,555,556
Quanzhou Dingwo Chuangfeng Investment Center (Limited Partnership)Addresses of individuals are not displayed.5,555,556
Chen HaiouAddresses of individuals are not displayed.201,497,286
Li ZonghaiAddresses of individuals are not displayed.198,239,536
CART Biotech LimitedAddresses of individuals are not displayed.198,139,536
Guo BingsenAddresses of individuals are not displayed.198,139,536
Redelle Holding LimitedAddresses of individuals are not displayed.198,139,536
Wang HuamaoAddresses of individuals are not displayed.198,239,536
He Xi Holdings LimitedAddresses of individuals are not displayed.198,139,536
Guo HuaqingAddresses of individuals are not displayed.200,618,536
Candock Holdings LimitedAddresses of individuals are not displayed.198,139,536
Accure Biotech LimitedAddresses of individuals are not displayed.198,139,536
YIJIE Biotech Holding LimitedAddresses of individuals are not displayed.198,139,536
Total number of shares in which a substantial shareholder is interested under sections 317 and 318209,731,842
 
24. Supplementary information: The percentage level of Ms. Xuehong Yang's interests in the shares of CARsgen Therapeutics Holdings Ltd. (the "Company") has decreased upon the cancellation of 7,228,000 treasury shares of the Company on July 30, 2026.
25. Log/Serial Number of the previous form:
26. Number of concert party document(s) under section 317 attached/uploaded: 1
A0000000000002158663.pdf
Date of filing this Form 1: 04/08/2026
(dd/mm/yyyy)